Patients Health and Wellbeing by Alzheimer and Sleep Apnea point of view

Jani Miettinen

2022/08/03

In this section I’m gathering projects related to Patient’s Health by Alzheimer and Sleep Apnea point of view. These projects utilizes hospital and open source data sources.

Research plan

On going articles

  1. Estimating the cost of Sleep Apnea

Shiny applications

  1. Shiny: Sleep Apnea Costs Visualization
  2. Shiny: Sleep Apnea Costs Calculator
  3. Shiny: Alzheimer patients timeline

Materials

  1. Data playbook: Sleep Revolution and IHME data

References

Armeni P, Borzoi L, Costa F, Donin G, and Gupta A. (2019) Cost-of-illness study of Obstructive Sleep Apnea Syndrome (OSAS) in Italy. Available: https://cergas.unibocconi.eu/sites/default/files/files/Cost-of-illness-study-of-Obstructive-Sleep-Apnea-Syndrome-%2528OSAS%2529-in-Italy_Report%25281%2529.pdf

Benjafield AV, Ayas NT, Eastwood PR, Heinzer R, Ip MSM, Morrell MJ, Nunez CM, Patel SR, Penzel T, Pépin JL, Peppard PE, Sinha S, Tufik S, Valentine K, Malhotra A. (2019) Estimation of the global prevalence and burden of obstructive sleep apnoea: a literature-based analysis. Lancet Respir Med. 2019 Aug;7(8):687-698. doi: 10.1016/S2213-2600(19)30198-5. Epub 2019 Jul 9. PMID: 31300334; PMCID: PMC7007763. Available: https://pubmed.ncbi.nlm.nih.gov/31300334/

Häppölä P, Havulinna A.S., Tasa T. et al. (2020) A data-driven medication score predicts 10-year mortality among aging adults. Sci Rep 10, 15760 (2020). https://doi.org/10.1038/s41598-020-72045-z

Kasai T. (2012) Sleep apnea and heart failure. J Cardiol. 2012 Aug;60(2):78-85. doi: 10.1016/j.jjcc.2012.05.013. Epub 2012 Jul 21. PMID: 22824295.

Lindberg, Perttu et al. (2014) Aivosairaudet ovat kalleimmat kansantautimme. Duodecim 2014;130:1721-30. Saatavilla: https://www.braincouncil.eu/wp-content/uploads/2020/06/Cost-of-Disorders-of-the-Brain-in-Europe-Finland.pdf

Miettinen, Jani (2013) Itsevalikoituminen verkkokyselytutkimuksen haasteena. Opinnäytetyö, Helsingin yliopisto. Saatavilla: https://helda.helsinki.fi/handle/10138/29260?show=full

Nordic Healthcare Group (2016) Paljon palveluita tarvitsevien asukkaiden palveluiden integraatio ja ennaltaehkäisy sote-uudistuksessa. Analyysi. Saatavilla: https://www2.nhg.fi/nhgfi/wp-content/blogs.dir/164/files/2016/11/NHG_Integraatio_uudessa_sotessa.pdf

Potsic WP. (1989) Obstructive sleep apnea. Pediatr Clin North Am. 1989 Dec;36(6):1435-42. doi: 10.1016/s0031-3955(16)36798-0. PMID: 2685722.

Rodenstein D. (2009) Sleep apnea: traffic and occupational accidents–individual risks, socioeconomic and legal implications. Respiration. 2009;78(3):241-8. doi: 10.1159/000222811. Epub 2009 May 30. PMID: 19494476.

Sharma RA, Varga AW, Bubu OM, Pirraglia E, Kam K, Parekh A, Wohlleber M, Miller MD, Andrade A, Lewis C, Tweardy S, Buj M, Yau PL, Sadda R, Mosconi L, Li Y, Butler T, Glodzik L, Fieremans E, Babb JS, Blennow K, Zetterberg H, Lu SE, Badia SG, Romero S, Rosenzweig I, Gosselin N, Jean-Louis G, Rapoport DM, de Leon MJ, Ayappa I, Osorio RS. (2017) Obstructive Sleep Apnea Severity Affects Amyloid Burden in Cognitively Normal Elderly. A Longitudinal Study. Am J Respir Crit Care Med. 2018 Apr 1;197(7):933-943. doi: 10.1164/rccm.201704-0704OC. PMID: 29125327; PMCID: PMC6020410. Available: https://pubmed.ncbi.nlm.nih.gov/29125327/

YLE Uutiset (2020) Aivosairauksista kertyy vuosittain jopa 11 miljardin lasku – Suuri osa aivoverenkiertohäiriöistä olisi estettävissä. Uutinen. Saatavilla: https://yle.fi/uutiset/3-11579183

R-packages

Duckdb R-package. Available: https://duckdb.org/

Shiny R-package. Available: https://shiny.rstudio.com/

I’m sure there will be more.